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Pure Encapsulations®

E.P.O. (evening primrose oil)

E.P.O. (evening primrose oil)

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E.P.O. (evening primrose oil)


Cold-pressed evening primrose seed for skin health and musculoskeletal comfort; contains 9% GLA‡


Benefits & Features

  • Supports the look and feel of healthy skin‡
  • Promotes healthy prostaglandin E1 production and cytokine activity which may help support joint comfort‡
  • GLA provides cardiovascular function support in women when combined with EPA/DHA‡
  • May provide premenstrual comfort‡
  • Source of the essential fatty acids including GLA
  • Produced using cold-pressed process without solvents
  • Convenient softgel capsule for easy dispensing
  • Made with high-quality ingredients backed by verifiable science


  • Ages 18 and up
  • Healthy skin support‡
  • Cardiovascular and joint comfort‡

Suggested Use:

As a dietary supplement, take 1 capsule, 1-4 times daily, with or between meals.


Science & Research

Verifiable Science:
Evening primrose oil (E.P.O.) is cold-pressed and produced without the use of any solvents. Used for centuries as nutritional support for a wide range of physiological functions, several studies have indicated that E.P.O. may help support the look and feel of healthy skin.1 A clinical trial reported that E.P.O. supported healthy skin through a modulation of IFN-gamma.2 Another study revealed that E.P.O. promoted skin health and led to a more favorable shift in eicosanoid metabolism.3 Other studies suggest that E.P.O. may support healthy lipid metabolism and may provide oxidative protection by promoting glutathione reductase and transferase activities.4 A clinical trial reported that GLA in combination with EPA/DHA significantly promoted healthy cardiovascular function in women.5 Additionally, E.P.O. may potentially be supportive of premenstrual comfort.6‡


  1. Muggli R. Int J Cosmet Sci. 2005 Aug;27(4):243-9.
  2. Yoon S, et al. Skin Pharmacol Appl Skin Physiol.2002 Jan-Feb;15(1):20-5.
  3. Yoshimoto-Furuie K, et al. Nephron. 1999 Feb;81(2):151-9.
  4. Lee SJ, et al. Intern J Dairy Tech. 2007. 60(1); 22-30.
  5. Laidlaw M, et al. Am J Clin Nut. 2003. 77(1); 37-42.
  6. Pruthi S, et al. Altern Med Rev. 2010 Apr;15(1):59-67.


Highlights: GMO Free


Additional Information

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Store in a cool, dry place.


  • Evening primrose oil is a cold-pressed oil produced without the use of any solvents


‡These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
†Provides weight management support as part of a healthy lifestyle with a reduced calorie diet and regular exercise.


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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.