Skip to product information
1 of 2

Seeking Health®

Active B12 5000

Active B12 5000

Regular price $25.99
Regular price Sale price $25.99
Sale Sold out
Active B12 5000



Key Benefits and Actions†

  • Potent dose of bioavailable B12 in a delicious lozenge
  • Healthy methylation and MTHFR support
  • Supports healthy homocysteine levels


Who Needs Active B12 5000
Your body prefers bioavailable nutrients. This means few (or no) enzymatic steps are required to transform it into a usable form. The two most bioactive forms of B12 are methylcobalamin and adenosylcobalamin.†

Bioavailability is particularly crucial when working to replenish vitamin B12 levels. Ideally, B12 is also in a format that supports optimal digestion and absorption, such as a lozenge.†

Active B12 5000 provides a potent dose of bioavailable vitamin B12 in a delicious, well-absorbed lozenge. Each serving contains a 5,000 mcg mixture of methylcobalamin and adenosylcobalamin.†

You need steady energy to feel your best. Vitamin B12 plays important roles in energy production and much more.†

Vitamin B12 is essential for:†

  • Cognitive function
  • Red blood cell formation
  • Methylation
  • Homocysteine recycling
  • Cardiovascular health
  • DNA production and expression
  • Nervous system health and development
  • Vitamin B12 deficiency is common. It is one of the most difficult nutrients for your body to absorb and utilize. Symptoms of vitamin B12 deficiency can include fatigue, memory issues, and tingling in your toes or fingers.

Factors such as genetic mutations, low stomach acid, a vegetarian or vegan diet, and insufficient intrinsic factor (pernicious anemia) can all contribute to low B12 levels. For these reasons, it’s critical to consume B12 in bioavailable, optimally-absorbed forms.†

Active B12 5000 provides bioactive forms of vitamin B12 that your body can readily recognize and utilize. These delicious lozenges are designed to be rapidly digested and absorbed through your intestines and cell walls.†

Most B12 dietary supplements contain the active ingredient cyanocobalamin. Before it can be used, your liver must first convert cyanocobalamin into an active form and discard the cyanide. In addition, it appears that the body uses methylcobalamin more efficiently than cyanocobalamin.†

Here at Seeking Health, you’ll never find the cyanide-containing form, cyanocobalamin. Instead, you’ll only find bioavailable forms of vitamin B12 that your body can quickly recognize and utilize.†

Active B12 5000 provides a potent dose of vitamin B12 in the bioactive forms of methylcobalamin and adenosylcobalamin. These delicious, well-absorbed lozenges support healthy methylation, MTHFR, and homocysteine levels.†

How much vitamin B12 do you need?

Everyone has different needs for vitamin B12. Work with a qualified healthcare professional to determine the best dose for your individual needs.

Active B12 5000 provides a potent dose of 5,000 mcg (5 mg) per serving. The lozenges can be broken down into halves or quarters if a smaller dose is desired.

For a lower dose of vitamin B12 per lozenge (1,000 mcg), consider Active B12 1000.
For a similar product without the methyl B12, consider Adeno B12.
For vitamin B12 in the form of hydroxocobalamin, consider Hydroxo B12.
It’s never been easier (or tastier!) to support optimal B12 levels in your body. Add Active B12 5000 to your methylation support protocol for optimal wellness.†


Key Ingredients In Active B12 5000

  • Vitamin B12: Included in two active coenzyme forms, methylcobalamin and adenosylcobalamin. These bioavailable forms help methylfolate donate methyl groups for optimal DNA expression. They also support the transformation of food energy into cellular energy.†


Why Active B12 5000 Works

Folate needs the help of vitamin B12 for proper methylation.†

Do you take methylfolate to support methylation and homocysteine metabolism? These processes cannot happen with methylfolate alone. They also require adequate B12.†

With the help of B12, supplemental methylfolate bypasses the MTHFR enzyme and is brought into the methylation pathway via the MTR enzyme. Ultimately, methylfolate donates its methyl groups to regulate DNA expression, healthy homocysteine levels, and much more.†

Without sufficient bioavailable B12, you cannot effectively break down the amino acid homocysteine to methionine. Your body needs methyl B12 and methylfolate for this to happen. Elevated homocysteine levels have been correlated with cardiovascular concerns.†

If you have an MTHFR genetic mutation, you may need additional support for methylation and recycling homocysteine to methionine. The human body uses methylcobalamin to carry out these functions.†

Adenosylcobalamin is a methyl-free, bioavailable form of B12. Also known as Adeno B12, it is found in your cells’ mitochondria to support energy production. Here, it acts as a coenzyme to create energy (ATP) from cholesterol, branched-chain amino acids, odd chain fatty acids, and propionate. It does this by converting a derivative of these compounds into succinyl-CoA. This compound can then enter the Krebs cycle to generate cellular energy (ATP).†

Methylcobalamin and adenosylcobalamin can both enter the cell’s cobalamin pool. When needed, your body pulls cobalamin from this pool to use in various processes, including methylation and homocysteine breakdown.†

Active B12 5000 provides a potent dose of methylcobalamin and adenosylcobalamin in a delicious, optimally-absorbed lozenge. For a lower dose, consider Active B12 1000. Because B12 needs folate to support proper methylation, be sure to pair Active B12 5000 with a bioactive form of folate, such as L-5-MTHF Lozenge.†

It’s never been tastier (or easier) to support healthy methylation, homocysteine levels, and energy!†


Active B12 5000
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin) 5000 mcg 208,333%
DV = Daily Value

Other Ingredients: Xylitol, ascorbyl palmitate, silica, and natural flavors.

MECOBALACTIVE® is a registered trademark of HealthTech BioActives SLU d.b.a. Ferrer HealthTech.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach by children.
Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use Active B12 5000

Suggested Use:
Take 1 lozenge daily or as directed by your healthcare provider. Lozenge may be broken into smaller pieces if a lower dosage is desired. Do not take within 5 hours of bedtime as it may interfere with sleep.

Children and pregnant or breastfeeding women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged.


HighlightsDairy Free, Egg Free, Fish Free, Gluten Free, GMO Free, Peanut Free, Sesame Free, Shellfish Free, Soy Free, Tree Nut Free, Wheat Free, No Artificial Colors, No Artificial Flavors, No Artificial Preservatives


†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

View full details
Labels and packaging may change without warning from manufacturer.
Please consult the actual product label for the most accurate product information and directions for proper use.
The Natural Alternative Nutrition Center does not provide medical advice or consultation. Consult your physician before ordering and/or using any product available on our website.
We do not guarantee carrier calculated deadlines for shipping.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.